Liquorice Root Found to Contain Anti-Diabetic Substance

ScienceDaily (Apr. 17, 2012). Researchers have discovered a promising anti-diabetic substance in the amorfrutin class of natural substances. It provides the raw material for liquorice candy, calms the stomach and alleviates diseases of the airways: liquorice root. Chosen as the “Medicinal plant 2012,” the root has been treasured in traditional healing since ancient times. Researchers […]

Circulating Levels of Phthalate Metabolites Are Associated With Prevalent Diabetes in the Elderly

Care.diabetesjournals.org: April 12, 2012. OBJECTIVE Phthalates are ubiquitous industrial high-volume chemicals known as ligands to peroxisome proliferator–activated receptors (PPARs). Because PPAR-γ agonists modulate insulin sensitivity and are used to treat type 2 diabetes, we investigated whether circulating levels of phthalate metabolites are related to prevalent type 2 diabetes. RESEARCH DESIGN AND METHODS A total of 1,016 subjects, […]

Diabetes Knowledge and Its Relationship With Achieving Treatment Recommendations in a National Sample of People With Type 2 Diabetes

Care.diabetesjournals.org: April 12, 2012. OBJECTIVE We examined the prevalence of knowledge of A1C, blood pressure, and LDL cholesterol (ABC) levels and goals among people with diabetes, its variation by patient characteristics, and whether knowledge was associated with achieving levels of ABC control recommended for the general diabetic population. RESEARCH DESIGN AND METHODS Data came from 1,233 adults […]

Why Shift Work and Sleeplessness Lead to Weight Gain and Diabetes

Working the night shift? Researchers now understand how night jobs — and chronic jet lag — can affect your insulin levels and your waistline. Healthland.time.com: By ALICE PARK, April 12, 2012 . Studies show that shift work and other sleep disturbances like jet lag can disrupt your body clock and increase the risks of obesity and diabetes. But, until now, researchers haven’t really […]

Bean and rice meals reduce postprandial glycemic response in adults with type 2 diabetes: a cross-over study

Nutrition Journal:  Sharon V Thompson, Donna M Winham and Andrea M Hutchins,  2012, 11:23 doi:10.1186/1475-2891-11-23. Around the world, beans and rice are commonly consumed together as a meal. With type 2 diabetes increasing, the effect of this traditional diet pattern on glycemic response has not been studied fully. Methods We evaluated the glycemic response of bean and rice traditional meals compared […]

Understanding Insulin Sensitivity and Diabetes

Nih.gov: April 9, 2012. A new discovery helps explain how adipose tissue (fat) affects insulin sensitivity and results in type 2 diabetes. The finding may lead to new strategies for treating the disease. Diabetes is a disorder in the way the body uses glucose, a sugar that serves as fuel for the body. When blood glucose […]

Towards a robust global framework for conduct and oversight of clinical trials

Ema.europa.eu, 16/04/2012. European Medicines Agency publishes reflection paper with practical guidance on the assurance of ethical and GCP standards in the conduct of clinical trials included in marketing authorisation applications submitted in the EU The European Medicines Agency today published the final reflection paper on ethical and good clinical practice (GCP) aspects of clinical trials of […]

Clinical Trials Need Major Remodeling

Nihrecord.od.nih.gov: By Carla Garnett, April 13, 2012. We need to rethink the clinical trials system—from the ground up. That’s what Dr. Robert Califf proposed at a recent Mind the Gap seminar, “Innovative Approaches to Clinical Trials.” “I hope to convince you that incremental changes in our clinical trials system will not be sufficient,” he said. “We […]

Envisioning a Transformed Clinical Trials Enterprise in the United States

Establishing an Agenda for 2020 – Workshop Summary Released: April 13, 2012 Type: Workshop Summary Topic: Biomedical and Health Research Activity: Forum on Drug Discovery, Development, and Translation Board: Board on Health Sciences Policy. There is growing recognition that the United States’ clinical trials enterprise (CTE) faces great challenges. There is a gap between what […]

FDA: Guidance for Acceptance of Foreign Clinical Studies Not Conducted Under an IND

Policymed: April 11, 2012. On April 28, 2008, the Food and Drug Administration (FDA) amended its regulations on the acceptance of foreign clinical studies not conducted under an investigational new drug application (IND) (“non-IND foreign clinical studies”) as support for an IND or a new drug application (NDA), abbreviated new drug application (ANDA), or a biologics […]

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